Yue (Mike) Yu
Columbia University · BME

Yue (Mike) Yu

Biomedical Engineering, Columbia University — hardware & software.

I'm an undergraduate biomedical engineer (B.S., expected May 2028; GPA 3.83, Dean's List) working at the intersection of flexible electronics fabrication, deep learning, and dexterous robotics.

I like building the full signal chain of an instrument — fabricating the electrode, writing the firmware that drives it, and training the model that makes sense of what comes back. I am currently working as an undergraduate reseearch at the Columbia Laboratory for Unconventional Electronics (CLUE) under Dr. Ioannis (John) Kymissis.

Research

Wearable diffuse optical tomography illustration

W-DOT — Wearable Diffuse Optical Tomography (in progress)

CLUE · Aug 2025 – Present

A wearable system using flexible LED–photodiode arrays to non-invasively screen for breast cancer by reconstructing optical absorption through tissue. Wrote STM32 firmware (STM32CubeIDE) for individual LED addressing, and optimized illumination/detection patterns to maximize source–detector coverage and SNR.

Flexible bioelectronicsSTM32 firmwareOptical imaging
Benchtop loop: syringe pump and oscilloscope

CSF Shunt Flow Sensor — Ion-Cloud Transit Sensing (in progress)

CLUE · Aug 2025 – Present

A four-electrode sensor for ventriculoperitoneal shunts: an upstream pair pulses the conductive CSF and the downstream pair times the ion cloud's transit, mapping to flow rate and revealing obstruction. Built the benchtop loop (NE-1000 syringe pump, artificial CSF, Keysight WaveGen + capture), characterized Pt–Ir electrodes via EIS, and designed a translational version with cleanroom metal deposition + Parylene-C.

MicrofabricationEISSignal analysis
Drawn-on-Skin conductive ink

Drawn-on-Skin Bioelectronics

Yu Research Group · Aug 2024 – Present

Conductive ink drawn directly on skin to capture EEG, ECG, and skin-impedance signals for stress detection and wearable diagnostics. Developing flexible DoS transistors, heaters, and pressure sensors, and mentoring incoming researchers in lab protocols.

Validation: 100% biocompatibility · 90% signal integrity at 50% stretch
Conductive inkStretchable electronicsBio-signals
NeuroTech EEG project

NeuroTech — Brain-Controlled Motion Classification

NeuroTech, Universum · Officer, Model Development · 2024–2025

Led 7 undergraduates applying AI/ML to brainwave data from commercial EEG headsets. Streamlined acquisition with an IRB-approved SOP over Lab Streaming Layer, and classified grasping motions with a Gaussian Mixture Model + K-Nearest Neighbors.

$5,000 seed funding · 0.005 s sync · EOH Visionary Impact Award
Brain–computer interfaceEEG / LSLGMM / KNN

Projects

Scatter plot of predicted vs. true age for the late-fusion brain age model

Multimodal Neuroimaging — Brain Age Estimation

BMEN 4545 · Deep Learning in Biomedical Imaging

SFCN (3D CNN) and a Vision Transformer with a 3D-CNN tokenizer stem, trained on 712 ADNI subjects with paired T1 + FLAIR MRI. Full preprocessing (N4 bias correction, MNI152 registration) and transfer learning from a UK Biobank checkpoint.

Best: independently-trained T1w + FLAIR combined via late fusion — R² 0.590 (vs. 0.56 for T1w alone)
PyTorch3D CNNViTADNITransfer learningMultimodal fusion

Read more →

Tendon-driven robotic hand

Multimodal Dexterous Hand (in progress)

CRAFT × SpikeATac · Robotic Manipulation

Integrating SpikeATac piezoelectric tactile sensors onto the fingertips of CRAFT, an open-source tendon-driven hand with hybrid hard–soft compliance, then designing a multimodal architecture that fuses touch + vision to train manipulation policies.

Tactile sensingMultimodal learningRobotics

SpikeATac ↗ CRAFT ↗

Publication & Award

Levitating magnetic insole prototype

Levitating Magnetic Insoles for Plantar Fasciitis

ISEF Finalist · first-author, peer-reviewed

Designed and tested a levitating sole using neodymium magnets to relieve plantar fasciitis — achieving 84.57 lbs of repulsion, an improvement over traditional EVA foam. Applied K-Means clustering to plantar-pressure and gait data to tune magnetic force across the sole for optimal redistribution.

Yu, Y. (2024). Levitating Magnetic Insoles: A Novel Approach to Alleviating Plantar Fasciitis Through the Reduction and Redistribution of Plantar Pressures. Journal of Innovations in Medical Research, 3(3), 14–35.

Biomedical EngineeringArduinoK-Means

Skills

Programming & SoftwarePython, C/C++, Java, MATLAB, Arduino, PCB design, Git
Machine LearningPyTorch, 3D CNNs, Vision Transformers, transfer learning, multimodal fusion, GMM/KNN, LLM pipelines
Microfabrication & CleanroomSputtering, e-beam deposition, Parylene-C, photolithography, electrode fabrication
Hardware & InstrumentationSTM32 firmware, oscilloscopes, function generators, EIS, signal acquisition, EEG (LSL)
Biomedical & ImagingMRI preprocessing (N4, MNI152, DICOM/NIfTI), diffuse optical tomography, PCR/CRISPR, fluorescent microscopy
LanguagesEnglish, Mandarin, Latin